TESE (Testicular Sperm Extraction)
Surgical Testicular Biopsy for Sperm Retrieval in Azoospermia
What is TESE (Testicular Sperm Extraction)?
TESE (Testicular Sperm Extraction) involves making small testicular incisions through which testicular parenchyma is excised and examined for spermatozoa. Conventional TESE takes multiple small biopsies from different areas of the testis; when sperm are found they are extracted for use in ICSI. TESE is suitable for both obstructive and non-obstructive azoospermia, with higher sperm retrieval rates than TESA for non-obstructive cases. The procedure is performed under general or spinal anaesthesia with a hospital stay of Day Care. Success rates reach 40–60% in appropriately selected patients at experienced centres.
How the Procedure Works
Scrotal Incision
Scrotal incision under local or general anaesthesia; testis exposed.
Multiple Biopsies
Multiple small biopsies (2–3 mm) excised from different areas of the testis.
Embryologist Assessment
Each biopsy placed in media and examined immediately by embryologist for spermatozoa.
Cryopreservation
Biopsy with spermatozoa identified; remaining tissue cryopreserved for future use.
Wound Closure
Testicular incisions closed; scrotum closed; scrotal support applied.
Outcomes
Who Needs This Treatment?
- →Higher sperm yield than needle aspiration (TESA) in non-obstructive azoospermia.
- →Multiple biopsy sites sample different areas of spermatogenic activity.
- →Day-case procedure with minimal morbidity.
- →Suitable for both obstructive and non-obstructive azoospermia.
- →Can be performed under local or general anaesthesia based on patient preference.
- →Spare tissue cryopreserved for future ICSI cycles avoiding repeat procedures.
"TESE opens the door to fatherhood for men with non-obstructive azoospermia. Even when hormones suggest very little sperm production, multiple targeted biopsies often find the spermatozoa needed to create a family."
— — Dr. Vipin Reddy, Consultant Urologist, Andrologist & Renal Transplant Surgeon
Common Questions
Frequently Asked
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