✦ Male Infertility Treatment

Micro-TESE

Q: What is the sperm retrieval rate for micro-TESE in Klinefelter syndrome?

Micro-TESE retrieves sperm in approximately 47% of men with Klinefelter syndrome; pre-operative testosterone optimisation may improve retrieval rates. Your consultant will provide specific guidance based on your individual clinical situation and recovery.

Q: Does micro-TESE affect testosterone levels?

Testosterone levels may transiently decrease after micro-TESE; the microscope-guided approach minimises Leydig cell damage compared to conventional TESE. Your consultant will provide specific guidance based on your individual clinical situation and recovery.

Q: Can micro-TESE be repeated if the first attempt fails?

Yes — repeat micro-TESE after 12–18 months is reasonable in selected patients; success rates are similar to the first attempt.

Microscopic Testicular Sperm Extraction — The Gold Standard for Non-Obstructive Azoospermia

2–4 Hours PROCEDURE

Day Care HOSPITAL STAY

40–60% SUCCESS RATE

3–7 Days RECOVERY

What is Micro-TESE?

Micro-TESE (Microsurgical Testicular Sperm Extraction) is the gold standard for sperm retrieval in non-obstructive azoospermia (NOA). Using an operating microscope at high magnification (16–25x), the testicular parenchyma is examined and seminiferous tubules that appear dilated (indicating active spermatogenesis) are selectively extracted. This targeted approach identifies spermatozoa in 40–60% of NOA patients while removing minimal testicular tissue, preserving testicular function. The procedure is performed under general or spinal anaesthesia with a hospital stay of Day Care. Success rates reach 40–60% in appropriately selected patients at experienced centres.

Men with non-obstructive azoospermia (Klinefelter syndrome, Sertoli-cell-only syndrome, hypospermatogenesis, cryptorchidism) who have failed conventional TESE or as primary sperm retrieval in NOA. Patients must be adequately fit for anaesthesia and free from active systemic infection before proceeding.

How the Procedure Works

Anaesthesia & Incision

General or spinal anaesthesia; large equatorial testicular incision made.

Microscopic Examination

Operating microscope (16–25x magnification) used to examine the testicular parenchyma systematically.

Tubule Identification & Extraction

Seminiferous tubule texture and diameter assessed; dilated tubules selectively extracted.

Real-Time Embryologist Assessment

All extracted tissue examined by embryologist in real time to identify spermatozoa.

Wound Closure

Only tissue with spermatozoa processed; testis closed primarily in layers.

Outcomes

2–4 HoursDURATION

Day CareHOSPITAL STAY

40–60%SUCCESS RATE

3–7 DaysFULL RECOVERY

Who Needs This Treatment?

→Highest sperm retrieval rate for non-obstructive azoospermia of any technique.
→Selective extraction minimises testicular parenchymal loss.
→Preserves Leydig cells protecting testosterone production post-procedure.
→Real-time embryologist assessment maximises sperm identification.
→Allows sperm retrieval in men with Klinefelter syndrome (47% success).
→Spare sperm cryopreserved for future ICSI cycles without repeat surgery.

"Micro-TESE is where technology meets hope. The operating microscope gives us the ability to find spermatozoa that conventional methods would miss — and for men with non-obstructive azoospermia, that can make all the difference."

— — Dr. Vipin Reddy, Consultant Urologist, Andrologist & Renal Transplant Surgeon

Common Questions

Frequently Asked

What is the sperm retrieval rate for micro-TESE in Klinefelter syndrome?+

Does micro-TESE affect testosterone levels?+

Can micro-TESE be repeated if the first attempt fails?+

Not sure which treatment is right for you?

Book a consultation with Dr. Vipin Reddy and get a personalised treatment plan.

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